Panama put the USA's hopes of qualifying for the Copa America knockout rounds on the line with a shock 2-1 victory over the hosts.
In a tumultuous Group C battle in Atlanta, both sides finished with 10 men, with Panama escaping with a victory that revived their hopes after their opening loss to Uruguay.
The game was tied in a moment of madness in the 18th minute when American winger Timothy Weah was sent off for a tackle on Panama defender Roderick Miller.
Although Folarin Balogun fired the USA ahead with a shot from the edge of the penalty area after 22 minutes, Panama got back on the scoresheet just minutes later on a strike from Cesar Blackman.
As the match progressed, however, Panama's one-man advantage began to take its toll on the tired American players.
With seven minutes to go, Jose Fajardo scored in emphatic fashion to put Panama ahead 2-1.
Late in the game, Adalberto Carrasquilla was sent off after a cynical foul on USA captain Christian Pulisic in the closing minutes.
The win means the U.S. may have to beat Uruguay in their final group game next Monday to advance to the quarterfinals. | BGNES