Russian strikes on Odessa have injured at least eight people and damaged a historical museum, AFP reports.
Photos released by city authorities and the museum show debris and shards of glass on the floor of the Odessa Museum of Fine Arts.
Some walls are cracked and some paintings appear to have been tossed to the ground by the force of the explosion.
Ukraine's deputy foreign minister, Emine Dzhepar, said she was "deeply outraged" by the strike.
"The deliberate destruction of cultural sites is a crime against Ukraine's heritage," she condemned, calling for "a strong international response and immediate action by UNESCO".
Acting museum director Kateryna Kulay said an assessment of the "(potential) damage, invisible to the naked eye" was currently underway. Most of the works on display have been "evacuated," said Oleg Kipper, a regional official.
"The drawings and paintings in the current exhibitions have not been damaged," he said on Telegram.
Kiev accused Moscow of firing four missiles and launching combat drones from Russian-occupied Ukrainian territory.
Eight people were wounded in the Odessa region, Ukrainian Interior Minister Igor Klimenko said.
The strikes also hit about twenty buildings and infrastructure sites, the nature of which is not specified.
Ukraine also fears Moscow will launch systematic attacks on its energy infrastructure, as it did last winter, forcing millions of people to go without heating and electricity.
Andriy Yermak, head of the Ukrainian president's administration, warned that the winter would be "very difficult." "Russia is preparing, so we have to prepare too," he said.
Kiev has asked its Western allies to bolster its air defences to counter fears of increased Russian strikes over the winter.
In Kherson Oblast, also in the south of the country, buildings were hit by a missile, Governor Oleksandr Prokudin said.
One of those buildings "was hit for the third time by the enemy," he said, adding that the strike wounded one resident.
The Ukrainian air force announced that "fifteen Shahed (unmanned aerial vehicles) and one X-59 guided air missile (had) been shot down." Finally, Ukraine reported that a Russian missile had killed 19 of its soldiers on 3 November.
On 5 November, Ukrainian President Volodymyr Zelensky announced that an investigation would be conducted into the circumstances of this "tragedy, which he said could have been avoided".
The Ukrainian security services announced that legal proceedings had been initiated for "negligent conduct of an official military person".
In southern Russia, two Ukrainian drones were shot down in the Voronezh region, causing no casualties or damage, according to regional governor Alexander Gusev. / BGNES
